A reader asks…
When my partner ejaculates in my vagina, it’s pretty uncomfortable–itchy and burny. We’ve stopped doing that, but I’m a little weirded out. Does this happen to other ladies out there with male partners?
To answer your question right off the bat: Yes, what you’re experiencing does happen to other people. There are a few possible causes, but the specifics of what you’re describing lead me to believe that one particular explanation may be more likely than the others.

This is not my theory, but there is pretty much no situation for which I do not have a Mean Girls gif on deck.
Before I share my theory, however, I want to make an important disclaimer: I am not a medical expert, and what I have to say is no substitute for medical advice. My intent is to provide you with some information and resources about what might be going on, but I strongly recommend following up with a physician or nurse practitioner to get a more definitive answer and hopefully some options for feeling better in the future.
Now that that’s out of the way, let’s get to it.
I would be remiss if I didn’t first acknowledge that itching and burning sensations in the genital area are a common red flag that can indicate a sexually transmitted infection. It’s important to get tested at least once per year, and more regularly if you have multiple partners. If you’re unsure of your STI status, I definitely recommend making an appointment to get checked just to be safe.
While it’s certainly possible that an STI is the culprit in your situation, the fact that you’re only experiencing discomfort after your partner ejaculates inside of you leads me to think that something else might be going on. Seminal plasma hypersensitivity (SPH), known more colloquially as a semen or sperm allergy, is a little-known but very real phenomenon that impacts up to 40,000 women in the United States. It occurs when a person’s body has an allergic reaction to one or more of the proteins found in semen. SPH varies in severity from person to person, but the most common symptoms are pain, discomfort, itching, burning, or swelling in or near parts of the body that have been exposed to semen. Sometimes the reaction spreads beyond the area that was directly exposed, and people experience hives or rashes all over their body. In extreme cases anaphylaxis, a life-threatening allergic reaction that compromises the airway, can also occur.
SPH can manifest in a number of different ways depending on a person’s body chemistry and level of sensitivity. Some people with SPH experience reactions to all semen, while others find that they react to one partner’s semen but not another’s. Some people experience a reaction the very first time they’re exposed to semen, while others develop a sensitivity to it later on in their sexual life. The good news is that SPH doesn’t appear to leave behind any lasting effects once the discomfort of the reaction wears off, and it does not have a negative effect on fertility.
Because it is a fairly rare condition, SPH is often misdiagnosed or written off as an STI or other bacterial infection. If you suspect that you have SPH, it’s important that you share your concerns with a medical care provider that specializes in gynecologic health. You also may need to advocate for yourself to ensure that they are fully considering all possible causes for what you’re experiencing, including SPH. SeminalPlasmaAllergy.Org, a website created by a woman with SPH to provide resources to others who have the condition, offers a free screening questionnaire you can take to evaluate your symptoms. It may be useful to bring along the results of the questionnaire to your medical appointment to use as a jumping-off point for conversations with your healthcare provider.
Unfortunately there’s no cure for SPH, but there are strategies for managing it. One solution that you’ve already discovered is avoidance, or preventing exposure to semen in the first place. The most effective way to achieve this is consistent condom use. The early withdrawal method (AKA “pulling out”) may also work for some couples, but depending on your level of sensitivity to semen the small amount of fluid your partner releases before ejaculating could still cause a reaction.
There is also some research out there about the effectiveness of a treatment called intravaginal graded challenge, wherein solutions of diluted semen are introduced into the vagina at set time intervals. As time goes on, the concentration of semen present in the solution gradually increases, building up the patient’s tolerance for exposure. When successful, the treatment results in desensitizing the body to the proteins in semen which cause the unwanted reaction, thereby making it possible for a person to have unprotected sex without discomfort. Research on this treatment is promising, but in order for the effects to be long-lasting repeated exposure to semen (i.e. very consistent sexual contact) is necessary.
Thank you for sharing your question. I know that this isn’t the most cheerful of theories, but I hope that the information I’ve provided is useful nonetheless. Please feel free to reach out to me with any follow-up questions via my Contact page (or just message me on Facebook if we know each other in person).
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